The pituri story: a review of the historical literature surrounding traditional Australian Aboriginal use of nicotine in Central Australia

Table 2 Comparison of blood nicotine concentrations (ng/ml) following four different methods of administration

Administration method	Period of exposure (min)	Peak blood concentration ng/ml	Concentration (ng/ml) at
			30 min	120 min
Cigarette smoking	12	15	10	6
Oral snuff	30	15	15	12
Chewing tobacco	30	14	14	12
Chewing nicotine gum (4 mg)	30	9	9	7

Data taken from Benowitz et al.[67]. Data represents average values for the same 10 subjects, each with previous nicotine exposure, prior to nicotine administration via differing methods.

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