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Table 4 Literatures reporting on toxicity studies for medicinal plants used by the Karen

From: Ethnomedicinal plants used for digestive system disorders by the Karen of northern Thailand

Scientific name Toxic effect
Acorus calamus L. acute toxicity in mice, LD50 = 221 g/kg [44]
Cassytha filiformis L. acute toxicity in mice, LD50 = 625.8 g/kg [45]
Celastrus paniculatus Willd. hyperactivity and loss of righting reflex in rat [46]
Euphorbia heterophylla L. increase leucopaenia in rat [47]
Euphorbia hirta L. leucocytosis, dullness, anorexia, stairy haircoat and 20% mortality in rat [47]
Flemingia macrophylla (Willd.) Merr. severe hypoglycemia followed by death within 24 hour after administration to mice [48]
Kaempferia parviflora Wall. ex Baker hepatotoxic to rat [49]
Senna alata (L.) Roxb. decrease hemoglobin and erythrocyte (RBC) count values in rats [36]
Senna occidentalis (L.) Link intestinal disturbance in long-term used in rats [50]
Thunbergia laurifolia Lindl. decrease red blood cell in male mice [51]
Zingiber montanum (J.König) Link ex A.Dietr. acute toxicity in mice, LD50 = 80 g/kg [52]
Zingiber officinale Roscoe embryo toxic to pregnant rats [53]
Centella asiatica (L.) Urb. no toxic effect in mice [54]
Curcuma longa L. no toxic effect in human [55]
Gmelina arborea Roxb. no toxic effect in rodents [56]
Psidium guajava L. no toxic effect in mice [57]
Punica granatum L. no toxic effect in rats [58]
Tamarindus indica L. no toxic effect in mice [59]