Table 6 Daily dosage in dry plant equivalent per kg metabolic body weight (g/kg0.75) for homemade single species herbal remedy reports (HSHR) with orally administered preparations. Italian speaking regions (ItR), German speaking cantons (GeC), and data from previous Swiss studies [22, 23] are compared, with converted animal dose and converted human dose
Plant species with ≥ 3 reported HSHR and documented dosage | Daily dose [g/kg0.75] | ||||
|---|---|---|---|---|---|
Arithmetic mean (median; minimum value- maximum value; number of UR for which daily dosage has been estimated) | Determined daily dose [g/kg0.75] in previous Swiss studies [22, 23] | Converted animal dose [g/kg0.75] [39] | Converted human daily dose [g/kg0.75] [40] | ||
ItR | GeC | ||||
Achillea millefolium L. Flos et herba cum flos | 0.25 (0.13; 0.08–0.53; 3) | - | −; − | 0.31 | |
Allium sativum L. Bulbus | 1.09 (0.61; 0.28–3.14; 9) | - | −; 1.12 | 0.16–0.23 | 0.09–0.17 |
Armoracia rusticana P. Gaertn. & al. Radix | - | 2.54 (1.18; 0.26–3.98; 3) | −; − | - | - |
Arnica montana L. Herba cum radice | 0.012 (0.004; 0.004–0.029; 3) | - | −; − | - | - |
Camellia sinensis (L.) O. Kuntze. Folium | - | 0.38 (0.39; 0.27–0.47; 5) | −; 0.64 | 1.67–6.67 | 0.22–0.33 |
Coffea spp. Semen | 1.67 (1.46; 0.31–5.31; 9) | 1.19 (0.16; 0.04–9.8; 7) | 0.37; 0.35 | - | - |
Foeniculum vulgare Mill. Semen | 0.07 (0.07; 0.03–0.16; 4) | - | 0.24; − | 0.2–0.4 | 0.2–0.3 |
Linum usitatissimum L. Semen | 5.79 (3.55; 0.8–15.6; 12) | - | 2.92; 5.16 | 0.39–1.55ct 0.98–1.96cv | 0.66 |
Malva neglecta Wallr. Folium et herba | 0.59 (0.59; 0.29–0.89; 5) | - | −; − | - | - |
Matricaria recutita L. Flos | 0.63 (0.90; 0.18–1.2; 7) | 0.27 (0.16; 0.03–0.60; 15) | 0.22; 1.12 | 0.04–0.09 p 0.19–0.39 r | 0.39–0.52 |
Matricaria recutita L. Herba | - | 1.32 (1.33; 0.13–2.47; 4) | −; − | - | - |
Oryza sativa L. Semen | 19.79 (17.54; 15.70–26.14; 3) | - | −; − | - | - |
Quercus robur L. Cortex | - | 1.17 (0.94; 0.008–2.82; 5) | −; − | 0.19–0.39 r, 0.09–0.19 p | 0.13 |
Rumex obtusifolius L. Radix | - | 0.84 (0.8; 0.16–1.57; 3) | −; 1.72 | - | - |
Thymus vulgaris L. Herba | - | 0.35 (0.25; 0.07–0.98; 9) | 2.47; − | 0.19–0.39 r | 0.04–0.26 |
Urtica dioica L. Herba | 13.84 (5.79; 1–41.67; 8) | 0.09 (0.08; 0.05–0.16; 4) | 2.39; 0.49 | 0.19–0.39 r | 0.35–0.52 |
Urtica urens L. Herba | 4.54 (1.00; 0.04–26.6; 11) | - | −; − | - | - |